Arterial Parameters and Elasticity Estimation in Common Carotid Artery Using Deep Learning Approach

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Author(s)

Anoop Kumar Patel 1,* Sanjay Kumar Jain 1

1. Department of Computer Engineering, NIT Kurukshetra, India

* Corresponding author.

DOI: https://doi.org/10.5815/ijigsp.2019.11.03

Received: 26 May 2019 / Revised: 12 Jun. 2019 / Accepted: 26 Jun. 2019 / Published: 8 Nov. 2019

Index Terms

Carotid Artery Segmentation, Extreme Learning Machine, Cardiovascular Disease, Auto-encoder, Overlapping block

Abstract

The risk of cardiovascular diseases is growing worldwide, and its early detection is necessary to reduce the level of risk. Structural parameters of the carotid artery as intima-media thickness and functional parameters such as arterial elasticity are directly associated with cardiovascular diseases. Segmentation of the carotid artery is required to measure the structural parameters and its temporal value that is used to estimate the arterial elasticity. This paper has two primary objectives: (i) Segmentation of the sequence of carotid artery ultrasound to measure temporal value of intima-media thickness and lumen-diameter, and (ii) Young’s modulus of elasticity estimation. The proposed segmentation method uses the contextual feature of the image pattern and is based on multi-layer extreme learning machine auto-encoder network. This segmentation method has two parts: (a) region of interest localization and (b) lumen-intima interface and media-adventitia interface detection at the far wall. ROI localization algorithm divides the ultrasound frame into columns and also divides each column into overlapping blocks, ensuring that every column has a region of interest block. A multi-layer extreme learning machine with auto-encoder is trained with labelled data and in testing; system classifies the blocks into ‘region of interest’ and ‘non-region of interest’. Pixels belonging to the region of interest are classified in the first part and a similar network-based method is proposed for lumen-intima and media-adventitia interface detection at the near wall of the carotid artery. Structural parameter of the artery, intima-media thickness and lumen diameter are measured in a sequence of images of the cardiac cycle. The temporal values of structural parameters are used to estimate the young’s modulus of elasticity.

Cite This Paper

Anoop Kumar Patel, Sanjay Kumar Jain, " Arterial Parameters and Elasticity Estimation in Common Carotid Artery Using Deep Learning Approach", International Journal of Image, Graphics and Signal Processing(IJIGSP), Vol.11, No.11, pp. 18-28, 2019. DOI: 10.5815/ijigsp.2019.11.03

Reference

[1]D. Mozaffarian, E. J. Benjamin, A. S. Go, D. K. Arnett, M. J. Blaha, M. Cushman, and et al. “Heart disease and stroke statistics-2016 update a report from the American Heart Association” American Heart Association: Circulation, vol. 31, No. 4, pp.e38-e48, 2016.

[2]J. Scott, “Pathophysiology and biochemistry of cardiovascular disease” Curr Opin Genet Dev. Vol. 14, No. 3, pp. 271-279, 2004.

[3]Q. Baoge, and Q. Tao, “Causes of changes in carotid intima-media thickness: a literature review” Cardiovascular ultrasound. Vol. 13, No. 1 p.46, Dec 2015.

[4]S. Lechareas, A. Yanni, S. Golemati, A. Chatziioannou, and D. Perrea, “Ultrasound and biochemical  diagnostic tools for the characterization of vulnerable carotid atherosclerotic plaque” Ultrasound Med Biol. Vol. 42, No. 1, pp. 31-43, Jan 2015.

[5]M. E. Boesen, D. Singh, B. K. Menon, and R. Frayne, “A systematic literature review of the effect of carotid atherosclerosis on local vessel stiffness and elasticity”. Atherosclerosis. Vol. 243, No. 1, pp. 211-222. Nov 2015.

[6]M. Seçil, C. Altay, A. Gülcü, H. Çeçe, A. Y. Göktay, and O. Dicle, “Automated measurement of intima-media thickness of carotid arteries in ultrasonography by computer software” Diagnostic and Interventional Radiology, Vol. 11, No. 2, p. 105, Jan 2005. 

[7]N. A. Shirwany, and M. Zou, “Arterial stiffness: a brief review” Acta Pharmacol Sin. Vol. 31, No. 10, pp. 1267-1276, Oct 2010.

[8]R. H. Selzer, W. J. Mack, P. L. Lee, H. Kwong-Fu, and H. N. Hodis, “Improved  common  carotid  elasticity  and intima-media  thickness  measurements  from  computer  analysis  of  sequential  ultrasound  frames”,  Atherosclerosis. Vol. 154, No. 1, pp. 185-193, Jan 2001.

[9]E. Messas, M. Pernot, and M. Couade, “Arterial wall elasticity: State of the art and future prospects”, Diagnostic and interventional imaging. Vol. 94, No.  5, pp. 561-569, May 2013.

[10]R. Weinstein, “Noninvasive carotid duplex ultrasound imaging for the evaluation and management of carotid atherosclerotic disease”, Hematol Oncol Clin North Am. Vol. 6, No. 5, pp. 1131-1139, Oct 1992.

[11]G-B. Huang, Q-Y. Zhu, and C-K. Siew “Extreme learning machine: Theory and applications” Neurocomputing. Vol. 70, No. 6, pp. 489-501, Dec 2006.

[12]G. R. Feng, G-B Huang, Q. P. Lin, and R. Gay, “Error minimized extreme learning machine with hidden nodes and incremental learning”. IEEE Trans Neural Netw Vol. 20, No. 8, pp. 1352-1357, Aug 2013.

[13]G-B. Huang, X. Ding, and H. M. Zhou, “Optimization method based extreme learning machine for classification” Neurocomputing. Vol. 74, No. 12, pp. 155–163, Dec 2010.

[14]G. B. Huang, H. Zhou, X. Ding, and R. Zhang, “Extreme learning machine for regression and multiclass classification”, IEEE Trans. Syst. Man Cybern. Part B: Cybern. Vol. 42, No. 2, pp. 513-529, Oct 2011.

[15]Y. Bengio, A. Courville, and P. “Representation learning: a review and new perspectives” IEEE Trans Pattern Anal Mach Intell. Vol. 35, No. 8, pp. 1798-828, Aug 2013. 

[16]L.L.C. Kasun, H. Zhou, G.-B. Huang, and C. M. Vong, “Representational learning with extreme learning machine for big data”, IEEE Intell. Syst. Vol. 28, No. 6, pp. 31-34, Dec 2013.

[17]H. Obeid, V. Ouedraogo, and M. Hallab, “Arterial Stiffness: A New Biomarker to be Measured”, Journal of Archives in Military Medicine. Vol. 5, No. 1, Feb 2017.

[18]R. M. Menchón-Lara, J. L. Sancho-Gómez, and A. Bueno-Crespo, “Early-stage atherosclerosis detection using deep learning over carotidultrasound images” Applied Soft Computing. Vol. 49, pp. 616-628, Dec 2016.

[19]R. M. Menchón-Lara and J. L. Sancho-Gómez, “Fully automatic segmentation of ultrasound common carotid artery images based on machine learning” Neurocomputing. Vol. 151, pp.161-167, Mar 2015.

[20]Q. Li, W. Zhang, X. Guan, Y. Bai, and J. Jia, “An improved approach for accurate and efficient measurement of common carotid artery intima-media thickness in ultrasound images”, BioMed research international, 2014.

[21]D.E. Ilea, C. Duffy, L. Kavanagh, A. Stanton, and P. F. Whelan, “Fully automated segmentation and tracking of the intima media thickness in ultrasound video sequences of the common carotid artery”, IEEE transactions on ultrasonics, ferroelectrics, and frequency control. Vol. 60, No. 1, pp. 158-177, Dec 2012.

[22]M. C. Bastida-Jumilla, R. M. Menchón-Lara, J. Morales-Sánchez, R. Verdú-Monedero, J. Larrey-Ruiz, and J. L. Sancho-Gómez, “Frequency-domain active contours solution to evaluate intima–media thickness of the common carotid artery”, Biomedical Signal Processing and Control. Vol. 16, pp. 68-79, Feb 2015.

[23]Q. Liang, I. Wendelhag, J. Wikstrand, and T. Gustavsson, “A multi scale dynamic programming procedure for boundary detection in ultrasonic artery images”, IEEE Trans. Med. Imaging. Vol. 19, No. 2, pp. 127-142, Feb 2000.

[24]C. Liguori, A. Paolillo, and A. Pietrosanto, “An automatic measurement system for the evaluation of carotid intima-media thickness”, IEEE Transactions on instrumentation and measurement. Vol. 50, No. 6, pp. 1684-1691, Dec 2001.

[25]F. Faita, V. Gemignani, E. Bianchini, C. Giannarelli, L. Ghiadoni, and M. Demi, “Real-time measurement system for evaluation of the carotid intima-media thickness with a robust edge operator”,  J. Ultrasound Med. Vol.  27, No. 9, pp. 1353–1361, Sep 2008.

[26]F. Molinari, G. Zeng, and J. S. Suri, “Intima-media thickness: setting a standard for a completely automated method of ultrasound measurement”, IEEE transactions on ultrasonics, ferroelectrics, and frequency control. Vol. 57, No. 5, pp. 1112-1124, May 2010.

[27]X. Xu, Y. Zhou, X. Cheng, E. Song, and G. Li, “Ultrasound intima-media segmentation using Hough transform and dual snake model”, Comput. Med. Imaging Graph. Vol. 36, No. 3, pp. 248-258, Apr 2012.

[28]S. Petroudi, C. Loizou, M. Pantziaris, and C. Pattichis, “Segmentation of the common carotid intima-media complex in ultrasound images using active contours”, IEEE Trans. Biomed. Eng. Vol. 59, No. 11, pp. 3060-3069, Nov 2012.

[29]R.M. Menchón-Lara, M. C. Bastida-Jumilla, J. Morales-Sánchez, and J. L. Sancho-Gómez, “Automatic detection of the intima-media thickness in ultrasound images of the common carotid artery using neural networks”. Medical and biological engineering & computing. Vol.  52, No. 2, pp. 169-181, Feb 2014.

[30]P.K. Kumar, T. Araki, J. Rajan, J. R. Laird, A. Nicolaides, and J. S. Suri, “State-of-the-art review on automated lumen and adventitial border delineation and its measurements in carotid ultrasound”, Computer methods and programs in biomedicine. Vol. 163, pp. 155-168, Sep 2018.

[31]Q. Liang, I. Wendelhag, J. Wikstrand, and T. Gustavsson, “A multiscale dynamic programming procedure for boundary detection in ultrasonic artery images”, IEEE Transactions on medical imaging. Vol. 19, No. 2, pp. 127-142, Feb 2000.

[32]A.C. Rossi, P.J. Brands, and  A. P. Hoeks, “Automatic localization of intimal and adventitial carotid artery layers with noninvasive ultrasound: a novel algorithm providing scan quality control”, Ultrasound in medicine & biology. Vol. 36, No. 3, pp. 467-479, Mar 2010.

[33]F. Destrempes, J. Meunier, M. F. Giroux, G. Soulez, and G. Cloutier, “Segmentation in ultrasonic B-mode images of healthy carotid arteries using mixtures of Nakagami distributions and stochastic optimization”, IEEE Transactions on Medical Imaging. Vol. 28, No. 2, p.215, Feb 2009.

[34]J. Shin, N. Tajbakhsh, R. Todd Hurst, C. B. Kendall, and J. Liang, “Automating carotid intima-media thickness video interpretation with convolutional neural networks” In Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition. pp. 2526-2535, 2016.

[35]C.P. Loizou, “A review of ultrasound common carotid artery image and video segmentation techniques”, Medical & biological engineering & computing. Vol.  52, No. 12, pp. 1073-1093, Dec 2014.