Classification of Non-Proliferative Diabetic Retinopathy Based on Segmented Exudates using K-Means Clustering

Full Text (PDF, 793KB), PP.1-8

Views: 0 Downloads: 0

Author(s)

Handayani Tjandrasa 1,* Isye Arieshanti 1 Radityo Anggoro 1

1. Department of Informatics Sepuluh Nopember Institute of Technology (ITS) Surabaya, Indonesia

* Corresponding author.

DOI: https://doi.org/10.5815/ijigsp.2015.01.01

Received: 30 Aug. 2014 / Revised: 9 Oct. 2014 / Accepted: 7 Nov. 2014 / Published: 8 Dec. 2014

Index Terms

Retinal fundus images, non-proliferative diabetic retinopathy, hard exudates, K-means clustering, classification, SVM, multilayer perceptron, RBF network

Abstract

Diabetic retinopathy is a severe complication retinal disease caused by advanced diabetes mellitus. Long suffering of this disease without threatment may cause blindness. Therefore, early detection of diabetic retinopathy is very important to prevent to become proliferative. One indication that a patient has diabetic retinopathy is the existence of hard exudates besides other indications such as microaneurysms and hemorrhages. In this study, the existence of hard exudates is applied to classify the moderate and severe grading of non-proliferative diabetic retinopathy in retinal fundus images. The hard exudates are segmented using K-means clustering. The segmented regions are extracted to obtain a feature vector which consists of the areas, the perimeters, the number of centroids and its standard deviation. Using three different classifiers, i.e. soft margin Support Vector Machine, Multilayer Perceptron, and Radial Basis Function Network, we achieve the accuracy of 89.29%, 91.07%, and 85.71% respectively, for 56 training data and 56 testing data of retinal images.

Cite This Paper

Handayani Tjandrasa, Isye Arieshanti, Radityo Anggoro,"Classification of Non-Proliferative Diabetic Retinopathy Based on Segmented Exudates using K-Means Clustering", IJIGSP, vol.7, no.1, pp.1-8, 2015. DOI: 10.5815/ijigsp.2015.01.01

Reference

[1]Fiona Harney, "Diabetic retinopathy," Complications of Diabetes. Medicine, vol.34, pp. 95-98, March 2006.

[2]Tomi Kauppi, Valentina Kalesnykiene, et al. DIARETDB1 diabetic retinopathy database and evaluation protocol.

[3]Abdulrahman A. Alghadyan, MD., "Diabetic retinopathy – An update," Department of Ophthalmology, Saudi Journal of Ophthalmology, vol. 25, pp. 99–111, 2011.

[4]M.M. Fraz, P. Remagnino, A. Hoppe, B. Uyyanonvara, A.R.Rudnicka, C.G. Owen, S.A. Barman, "Blood vessel segmentation methodologies in retinal images-A survey," Computer Methods and Programs in Biomedicine, vol. 108, pp. 407-433, 2012.

[5]Wong Li Yun, U.Rajendra Acharya, Y.V.Venkatesh, Caroline Chee, Lim Choo Min, E.Y.K. Ng., "Identification of different stages of diabetic retinopathy using retinal optical images," Information Sciences. vol. 178, pp. 106-121, 2008.

[6]Kanika Verma, Prakash Deep, and A.G. Ramakrishnan, "Detection and Classification of Diabetic Retinopathy using Retinal Images," INDICON, 2011 Annual IEEE.

[7]Vesna Zeljković, Milena Bojic, Claude Tameze, Ventzeslav Valev. "Classification Algorithm of Retina Images of Diabetic Patients Based on Exudates Detection," HPCS, IEEE 2012.

[8]Handayani Tjandrasa, A.Y. Wijaya, I. Arieshanti, N. D. Salyasari, "Segmentation of Hard Exudates in Retinal Fundus Images Using Fuzzy C-Means Clustering with Spatial Correlation," The Proc. of The 7th ICTS, Bali, May 15th-16th, 2013.

[9]C. Kose, U. Sevik, C. Ikibas, H. Erdol. Simple methods for segmentation and measurement of diabetic retinopathy lesions in retinal fundus images. Computer Methods and Program in Biomedicine, 2011.

[10]D.Welfer, J. Scharcanski, D.R. Marinho. "A coarse-to-fine strategy for automatically detecting exudates in color eye fundus images," Computerized Medical Imaging and Graphics, vol. 34, pp. 228-235, 2010.

[11]Handayani Tjandrasa, R. E. Putra, A. Y. Wijaya, I. Arieshanti, "Classification of Non-Proliferative Diabetic Retinopathy Based on Hard Exudates Using Soft Margin SVM," The Proceedings of 2013 IEEE International Conference on Control System, Computing and Engineering ((ICCSCE 2013), Penang, 2013.

[12]Gunn, S. R.,"Support Vector Machine for Classification and Regression," Technical Report, University of South Hampton. 1998.

[13]Tom Mitchell. Machine Learning. Singapore: McGraw-Hill Companies Inc. 1997.

[14]MESSIDOR: Methods for Evaluating Segmentation and Indexing techniques Dedicated to Retinal Ophthalmology, http://messidor.crihan.fr/index-en.php, 2004.

[15]Handayani Tjandrasa, Ari Wijayanti, Nanik Suciati. "Optic Nerve Head Segmentation Using Hough Transform and Active Contours," TELKOMNIKA, vol.10, pp. 531-536, 2012.

[16]D. Welfer, J. Scharcanski, C.M. Kitamura, M.M.D. Pizzol, L.W.B. Ludwig, D.R. Marinho. Segmentation of the optic disk in color eye fundus images using an adaptive morphological approach. Computers in Biology and Medicine, 40, 2010, 124–137.

[17]Malaya Kumar Nath, and Samarendra Dandapat, "Techniques of glaucoma detection from color fundus images: a review," I.J. Image, Graphics and Signal Processing, vol.9, pp. 44-51, 2012.

[18]Akara Sopharak, Bunyarit Uyyanonvara, and Sarah Barman, "Fine microaneurysm detection from non-dilated diabetic retinopathy retinal images using a hybrid approach", WCE 2012, London, U.K., Vol II, July 4 - 6, 2012.

[19]Sergio Bortolin Junior, and Daniel Welfer, "Automatic detection of microaneurysms and hemorrhages in color eye fundus images," International Journal of Computer Science & Information Technology (IJCSIT) Vol 5, No 5, October 2013.

[20]Xu Wen-Hua, "Detection of microaneurysms in bifrequency space based on SVM," IEEE, 978-1-4577-0321-8/11/2011, pp.1432-1435, 2011.

[21]M. Usman Akram, Maryam Mubbashar, Anam Usman, "Automated system for macula detection in digital retinal images," IEEE International conference on Information and Communication Technologies, pp. 1- 5.July 2011.